ChesterRep

    An evaluation of Advice 4 Youth: A health and support service for young people

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    This report discusses and evaluates the work of Advice 4 Youth - in particular it seeks to develop effective and efficient systems for routine data collection, provide data on uptake of services by young people, analyse data to reveal a pattern of useage in relation to key variables, and assess the general progress of Advice 4 Youth.North Cheshire Health

    Exploring colorectal cancer patients' perceptions of the quality of their care

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    This report discusses the local situation in Halton with regard to colorectal cancer care by exploring how patients perceived the quality of their care.Widnes Primary Care Grou

    Becoming part of the team: Female student athletes’ engagement in initiation activities.

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    Accepted author manuscript version reprinted, by permission, from Human Kinetics, 2018. © Human Kinetics, Inc.The aim of the present research was to explore female student athletes’ participation in initiation activities specifically to examining whether activities in the United Kingdom followed similar trends to those reported elsewhere. A sample of eight female athletes, representing both traditional and non-traditional team and individual sports (M age = 20 years 3 months, SD = 1 year 3 months) who met inclusion criteria of having taken part in an initiation ceremony consented to participate in a semi structured interview. Thematic content analysis resulted in the emergence of six higher order themes represented by two general dimensions, the initiation event and initiation outcomes. Findings indicated that female student athletes’ initiation activities encompassed discrete stages as they moved from team newcomer to accepted team member. Of particular concern is the direct and indirect role of alcohol within these events and the health and behavioural risks

    Quantification of the pressures generated during insertion of an epidural needle in labouring women of varying body mass indices

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    Heighten Science Publications Corporation (HSPC) is pleased at the constructive and collaborative manner in which we are able to develop a liaison with University of Chester. HSPC is an Open Access publisher of scientific journals. As we continue to grow, HSPC along with the editors who help us run our Journals, continue to maintain the right balance between objectives of the scholars and long term sustainability for each of our journals. One of the important objective of any scholar is to reach more readers. HSPC helps to fulfil this objective by sharing your research and accomplishments to a wider audience and to make you more visible in your field. We are committed to provide hassle-free and rapid publication services to all the scholars. Please contact: info@heighpubs.us to know the appropriate journal for your research area. You can also visit: www.heighpubs.org/journals.php to choose a journal according to your research area of interest. HSPC wishes you a successful research career. Thank you!Objective: The primary aim of this study was to measure pressure generated on a Tuohy needle during the epidural procedure in labouring women of varying body mass indices (BMI) with a view of utilising the data for the future development of a high fi delity epidural simulator. High-fi delity epidural simulators have a role in improving training and safety but current simulators lack a realistic experience and can be improved. Methods: This study was approved by the National Research Ethics Service Committee South Central, Portsmouth (REC reference 11/SC/0196). After informed consent epidural needle insertion pressure was measured using a Portex 16-gauge Tuohy needle, loss-of-resistance syringe, a three-way tap, pressure transducer and a custom-designed wireless transmitter. This was performed in four groups of labouring women, stratified according to BMI kg/m2: 18-24.9; 25-34.9; 35-44.9 and >=45. One-way ANOVA was used to compare difference in needle insertion pressure between the BMI groups. A paired t-test was performed between BMI group 18-24.9 and the three other BMI groups. Ultrasound images of the lumbar spine were undertaken prior to the epidural procedure and lumbar magnetic resonance imaging (MRI) was performed within 72h post-delivery. These images will be used in the development of a high fi delity epidural simulator. Results: The mean epidural needle insertion pressure of labouring women with BMI 18-24.9 was 461mmHg; BMI 25-34.9 was 430mmHg; BMI 35-44.9 was 415mmHg and BMI >=45 was 376mmHg, (p=0.52). Conclusion: Although statistically insignifi cant, the study did show a decreasing trend of epidural insertion pressure with increasing body mass indices

    Pemphigus is associated with KIR3DL2 expression levels and provides evidence that KIR3DL2 may bind HLA-A3 and A11 in vivo.

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    This is the peer reviewed version of the following article:Augusto, D. G., O'Connor, G. M., Lobo-Alves, S. C., Bass, S., Martin, M. P., Carrington, M., . . . Petzl-Erler, M. L. (2015). Pemphigus is associated with KIR3DL2 expression levels and provides evidence that KIR3DL2 may bind HLA-A3 and A11 in vivo. European Journal of Immunology, 45(7), 2052-2060, which has been published in final form at DOI: 10.1002/eji.201445324. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-ArchivingAlthough HLA-A3 and A11 have been reported to be ligands for KIR3DL2, evidence for any in vivo relevance of this interaction is still missing. To explore the functional importance of KIR3DL2 allelic variation, we analyzed the autoimmune disease pemphigus foliaceus, previously associated (lower risk) with activating KIR genes. KIR3DL2*001 was increased in patients (odds ratio (OR) = 2.04; p = 0.007). The risk was higher for the presence of both KIR3DL2*001 and HLA-A3 or A11 (OR = 3.76, p = 0.013), providing the first evidence that HLA-A3 and A11 may interact with KIR3DL2 in vivo. The nonsynonymous single nucleotide polymorphism 1190T (rs3745902) was associated with protection (OR = 0.52, p = 0.018). This SNP results in a threonine-to-methionine substitution. Individuals who have methionine in this position exhibit a lower percentage of KIR3DL2-positive natural killer (NK) cells and also lower intensity of KIR3DL2 on expressing natural killer cells; additionally, we show that the expression of KIR3DL2 is independent of other killer cell immunoglobulin-like receptors. Pemphigus foliaceus is a very unique complex disease strongly associated with immune-related genes. It is the only autoimmune disease known to be endemic, showing a strong correlation with environmental factors. Our data demonstrate that this relatively unknown autoimmune disease may facilitate understanding of the molecular mechanisms of KIR3DL2 ligand recognition

    Gertrude Elles: the pioneering graptolite geologist in a woolly hat. Her career, achievements and personal reflections from her family and colleagues

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    From Crossref journal articles via Jisc Publications RouterHistory: epub 2020-10-26, issued 2020-10-26AbstractGertrude Elles gained worldwide renown for her seminal work with Ethel Wood on A Monograph of British Graptolites, which is still used today. She gained the MBE, pioneered female geological education, became the first female reader in Cambridge University and one of the first tranche of female Fellows of the Geological Society in 1919. An eccentric with a vast array of hats, PhD students and lodgers, she was a stalwart member of the Sedgwick Club and life member of the British Federation of University Women. She wrote obituaries for colleagues describing their achievements with humour and good nature. Her family describe her as ‘a fabulous woman’ with a huge range of interests including archaeology, botany and music. She related her geological and botanical knowledge in showing a nephew that plants growing along the Moine Thrust reflected change in the underlying rocks. Cambridge colleagues recall her as a ‘marvellous and well-respected figure’ who caused some amusement by her big old cluttered table from which she swept away material making room for new samples (and work for technicians). She died in 1960 in her beloved Scotland. However, her legacy survives in the classification of a group of fossils extinct for nearly 400 myr

    Corrigendum: Neural Correlates of Theory of Mind Are Preserved in Young Women With Anorexia Nervosa

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    From Frontiers via Jisc Publications RouterHistory: collection 2020, received 2020-10-14, accepted 2020-11-09, epub 2020-11-30Publication status: Publishe

    Patterns of Parenting, Class Relations and Inequalities in Education and Leisure: A Grounded Theory

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    This thesis is available to view in print at Seaborne Library, University of Chester, Parkgate Road, Chester, CH1 4BJ.The class structure of Britain has changed considerably since the 1970s. The gap between the rich and poor has grown, and many individuals can no longer be classified into traditional middle- and working-class categories. Despite polarisation and fragmentation, however, social class has continued to shapes individuals’ daily lives and life-chances. There are distinct class inequalities in education and leisure that appear to be resistant to intervention. Governments and other public organisations have invested considerable funds and deployed various policies, but individuals from affluent backgrounds continue to do better in the education system and be more active in their leisure time than individuals from deprived backgrounds. Academics have also turned their attention to class inequalities in education and leisure, especially of late. Research indicates that such inequalities emerge during early childhood and remain through youth and into adulthood. This, along with evidence of the limited effectiveness of interventions delivered through schools, has made one thing clear: to explain the production and reproduction of class inequalities in education and leisure and do something about them through policy, researchers and governments must look to the family. The ways in which parents from different social classes are involved and invest in their children’s education and leisure have been researched quite extensively. However, the findings in many of the studies are un-integrated and de-contextualised. In addition, much of the research is deductive – academics have tended to test theories and the significance particular family variables and processes. This thesis, therefore, set out to produce a grounded theory of class-specific patterns of parenting in relation to children’s education and leisure. Semi-structured interviews were conducted with a case study of parents and children from a small city in the north-west of England. Two main social classes emerged out of the case study, a group tentatively described as an ‘under-class’ and a middle-class divided into fractions. It was found that social class impacted upon several areas of family life, and differences in these areas of family life clustered together to form class-specific patterns of parenting. The under-class pattern of parenting was conceptualised as ‘essential assistance’. It conveys the present-centred and basic involvement of the parents – they did not think a great deal about the future but did what was necessary to keep their children up with their peers on a day-to-day basis. The middle-class pattern of parenting was conceptualised as ‘concerted cultivation’. It conveys the forward-thinking and deliberate nature of the parents’ involvement. Also, the meticulous lengths to which the parents went – every aspect of their children’s development was open to pruning. The middle-class parents were involved in their children’s education and leisure in similar ways, but to different degrees. Thus, concerted cultivation can be regarded as gradational. Class-specific patterns of parenting can be linked to the production of class-related patterns of inequality. Through essential assistance and concerted cultivation, under-class and middle-class parents condition their children to think and act in particular ways. More specifically, they furnish their children with different skills, preferences and mentalities. A detailed discussion of the theoretical and policy implications of these patterns of parenting is provided in the conclusion to the thesis

    A Christian Case for Farmed Animal Welfare

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    From MDPI via Jisc Publications RouterHistory: accepted 2019-12-08, pub-electronic 2019-12-11Publication status: PublishedFunder: Arts and Humanities Research Council; Grant(s): AH/R014752/1It is now common to blame Christianity for broader society’s general inattention to the needs and comfort of animals in general, and farmed animals in particular. This critique of Christianity claims that certain biblical themes and particular biblical passages form the foundation for an anti-animal position that Christianity has imposed on Christians and on wider Western society. This article concedes that Christianity has often been used to justify exploitation of animals, but argues that it is a mistake to consider Christianity inevitably opposed to concern for animals. After reviewing the views of critics such as Lynn White Jr., Peter Singer, and Tom Regan, the article demonstrates the complexity of interpreting biblical passages and the possibility of readings that affirm the importance of treating animals well. It shows that Christians have indeed been advocates for animals, notably in relation to the first legislation against animal cruelty in the early nineteenth century and the formation of the RSPCA. Finally, it proposes a constructive framework for a Christian ethics of farmed animal welfare that could provide the basis for Christian action to reduce consumption of animals and shift to higher welfare sources of animal products

    THE HEALTH IMPACT OF SCAMS

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    From Crossref via Jisc Publications RouterHistory: epub 2019-11-08, ppub 2019-11-08Article version: VoRAbstract This presentation will offer new and alternate insights into ‘scams’ and the health effects of fraud on older people. It reports data captured from a Mass Observation Project “Directive” focusing on scams and their impact on individuals. Eighty “Observers’” aged 50 and over responded to the “Directive”. Responses indicate that falling victim to a scam may have negative impacts on individuals’ mental wellbeing, self-esteem and relationships with others. Data analysis also identified that fear of victimisation can also affect individuals, resulting in worry, anxiety and maladaptive coping strategies. Offering a sociology of health perspective, we will focus is on these health impacts of scams and the legitimisation of the issue as a socio-political problem. We will also highlight additional important areas for consideration, such as the absence of a common understanding of the concept and nomenclature of ‘scam’, and the ‘vagaries of scams’ by presenting a typology of scams
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